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Generic name: darunavir and cobicistat

Brand names: Rezolsta

Class: Combined PI (protease inhibitor) tablets


Common: headache, diarrhoea, nausea, allergic reactions such as rash, itching, and severe swelling of the skin, lips or eyes, decreased appetite, abnormal dreams, vomiting, pain or swelling of the belly, indigestion, flatulence, muscle pain, muscle cramps or weakness, bone problems, tiredness, liver problems, diabetes.

Rare: severe rash, pancreatitis.


Tablet comprising 800mg darunavir and 150mg cobicistat. Cobicistat is a booster drug, which boosts the effect of darunavir.

Take one tablet a day.

Ritonavir is also approved for use as an anti-HIV drug at a dose of 600mg twice a day, but it is no longer used in this way.


Take with food.

*Last reviewed on 25/09/2015 Next review: 25/09/2018

Any questions? Email feedback@tht.org.uk Information included on this website was correct at the time of publication.

Data and image supplied by NAM.